Ah, Cannabinoids. Did you know that Cannabis produces hundreds of cannabinoids. How many exactly is hard to say. Many reports conducted have suggested that they’re around 113 naturally occurring cannabinoids found in the cannabis plant. What is a cannabinoid exactly? Well, I’m sure you’re familiar with the two that go by THC and CBD. Cannabinoids are natural components found in the hemp or marijuana plant. These various cannabinoids interact with the user by accessing receptors that are spread throughout our entire body that are actually meant to work with cannabinoids.
Before we dive into receptors and how they work with cannabinoids it is important to understand the endocannabinoid system. This system is made up of a network of receptors spread throughout our entire body that help regulate our immune system, mood, pain sensation, sleep patterns, and ultimately help bring us back to homeostasis. For more on understanding the Endocannabinoid system we recommend reading one of our latest articles that goes more into depth on this remarkable system. Anyway, the two known receptors that work with cannabinoids are referred to a CB-1 and CB-2 receptors. First we’ll take a closer look into the CB-1 receptor. This receptor is located mainly throughout our brain and central nervous system. More specifically, CB-1 receptors work with motor activity, appetite, motor coordination, immune cells, short term memory, and pain reception. Next, we have our CB-2 receptor that are more concentrated throughout the peripheral organs, immune cells, and the gastrointestinal tract. More specifically, our CB-2 receptor works with gut, kidneys, pancreas, liver, skeletal muscle, bone, eyes, skin, tumors, reproductive system, immune system, respiratory tract, and our cardiovascular system. Sounds pretty important huh?
Along Came Cannabinoids
The importance of cannabinoids, our Endocannabinoid system, and our CB-1, CB-2 receptors. All three are of vital importance and need one another to keep us at homeostasis. The Endocannabinoid system produces receptors known as CB-1 and CB-2. However, for years scientists were dumbfounded on why these receptors were in place and what they were meant for. Then, along came cannabinoids. Cannabinoids found in the hemp or marijuana plant were ultimately what ended up interacting with these receptors spread throughout our entire body.